NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
The authors use an integrative clustering approach to identify two laryngeal cancer clusters with distinct prognosis and show that mutations damaging the NSD1 and NSD2 methyltransferases segregate to the cluster with favorable prognosis, and independently predict longer survival in patients with lar...
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Bibliographic Details
| Main Authors: |
Suraj Peri,
Evgeny Izumchenko,
Adrian D. Schubert,
Michael J. Slifker,
Karen Ruth,
Ilya G. Serebriiskii,
Theresa Guo,
Barbara A. Burtness,
Ranee Mehra,
Eric A. Ross,
David Sidransky,
Erica A. Golemis |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2017-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-017-01877-7
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