Homology modeling of mosquito cytochrome P450 enzymes involved in pyrethroid metabolism: insights into differences in substrate selectivity

<p>Abstract</p> <p>Background</p> <p>Cytochrome P450 enzymes (P450s) have been implicated in insecticide resistance. <it>Anopheles minumus </it>mosquito P450 isoforms CYP6AA3 and CYP6P7 are capable of metabolizing pyrethroid insecticides, however CYP6P8 lack...

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Bibliographic Details
Main Authors: Rongnoparut Pornpimol, Jenwitheesuk Ekachai, Lertkiatmongkol Panida
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/4/321