Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS

Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS

Digoxin (DIG) is a positive inotropic drug with a narrow therapeutic window that is used in the clinic for heart failure. The active efflux transporter of DIG, P-glycoprotein (P-gp), mediates DIG absorption and excretion in rats and humans. Up to date, several studies have shown that the ginger and...

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Bibliographic Details
Main Authors: Chao Li, Dahu Liang, Yanhao Liu, Chaozhuang Shen, Xiaohu Wang, Bin Yang, Xianghong Li, Weijia Wang, Maodi Xu, Zhichen Pu, Hua Hu, Zijing Wu, Haitang Xie, Hua Sun
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2021/2673183

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