The early metabolomic response of adipose tissue during acute cold exposure in mice

The early metabolomic response of adipose tissue during acute cold exposure in mice

Abstract To maintain core body temperature in cold conditions, mammals activate a complex multi-organ metabolic response for heat production. White adipose tissue (WAT) primarily functions as an energy reservoir, while brown adipose tissue (BAT) is activated during cold exposure to generate heat fro...

Full description

Bibliographic Details
Main Authors:	Xiyuan Lu, Ashley Solmonson, Alessia Lodi, Sara M. Nowinski, Enrique Sentandreu, Christopher L. Riley, Edward M. Mills, Stefano Tiziani
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-03108-x

Similar Items

Stable Isotope Tracing Metabolomics to Investigate the Metabolic Activity of Bioactive Compounds for Cancer Prevention and Treatment
by: Feroza K. Choudhury, et al.
Published: (2020-08-01)

Effects of cold exposure on metabolites in brown adipose tissue of rats
by: Yuka Hiroshima, et al.
Published: (2018-06-01)

Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism
by: Alessia Lodi, et al.
Published: (2017-06-01)

The Combined Treatment With the FLT3-Inhibitor AC220 and the Complex I Inhibitor IACS-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells
by: Xiyuan Lu, et al.
Published: (2021-08-01)

Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.
by: Stefano Tiziani, et al.
Published: (2009-01-01)

Correction: Metabolomic Profiling of Drug Responses in Acute Myeloid Leukaemia Cell Lines
by: Stefano Tiziani, et al.
Published: (2009-01-01)

Correction: Metabolomic Profiling of Drug Responses in Acute Myeloid Leukaemia Cell Lines.
by: Stefano Tiziani, et al.
Published: (2009-01-01)

Transcriptional Response of Subcutaneous White Adipose Tissue to Acute Cold Exposure in Mice
by: Xiaojuan Liang, et al.
Published: (2019-08-01)

Responses of the insulin signaling pathways in the brown adipose tissue of rats following cold exposure.
by: Xiaofei Wang, et al.
Published: (2014-01-01)

Acute and chronic cold exposure differentially affects the browning of porcine white adipose tissue
by: Y. Gao, et al.
Published: (2018-01-01)

Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
by: Rekha Narasimhan, et al.
Published: (2018-08-01)

Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver.
by: Andrew M Shore, et al.
Published: (2013-01-01)

Predicting and Quantifying Antagonistic Effects of Natural Compounds Given with Chemotherapeutic Agents: Applications for High-Throughput Screening
by: G. Lavender Hackman, et al.
Published: (2020-12-01)

Long-term intermittent cold exposure affects peri-ovarian adipose tissue and ovarian microenvironment in rats
by: Li Zhang, et al.
Published: (2021-08-01)

Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice
by: Sujoy Ghosh, et al.
Published: (2021-07-01)

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
by: Wieneke Dijk, et al.
Published: (2015-10-01)

CXCL5 secreted from macrophages during cold exposure mediates white adipose tissue browning
by: Dabin Lee, et al.
Published: (2021-01-01)

Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment.
by: Alessia Lodi, et al.
Published: (2011-01-01)

Long-term intermittent cold exposure regulates glucose homeostasis via intervening metabolism of adipose tissue in mice
by: ZHOU Xin, et al.
Published: (2019-06-01)

Transcriptomic and metabolomic profiling of chicken adipose tissue in response to insulin neutralization and fasting
by: Ji Bo, et al.
Published: (2012-08-01)

Chronic cold exposure induces autophagy to promote fatty acid oxidation, mitochondrial turnover, and thermogenesis in brown adipose tissue
by: Winifred W. Yau, et al.
Published: (2021-05-01)

Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics
by: Stefano Tiziani, et al.
Published: (2009-03-01)

Continuous cold exposure induces an anti-inflammatory response in mesenteric adipose tissue associated with catecholamine production and thermogenin expression in rats
by: Vargovic P., et al.
Published: (2016-07-01)

Impaired HMG-CoA Reductase Activity Caused by Genetic Variants or Statin Exposure: Impact on Human Adipose Tissue, β-Cells and Metabolome
by: Assel Sarsenbayeva, et al.
Published: (2021-08-01)

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis
by: Chandramohan Chitraju, et al.
Published: (2020-11-01)

Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
by: Ziye Xu, et al.
Published: (2019-09-01)

Metabolomics analysis of plasma and adipose tissue samples from mice orally administered with polydextrose and correlations with cecal microbiota
by: Markku Tapani Saarinen, et al.
Published: (2020-12-01)

Cold Induced Depot-Specific Browning in Ferret Aortic Perivascular Adipose Tissue
by: Bàrbara Reynés, et al.
Published: (2019-09-01)

Brown Adipose Tissue and Skeletal Muscle 18F-FDG Activity After a Personalized Cold Exposure Is Not Associated With Cold-Induced Thermogenesis and Nutrient Oxidation Rates in Young Healthy Adults
by: Guillermo Sanchez-Delgado, et al.
Published: (2018-11-01)

R-MetaboList 2: A Flexible Tool for Metabolite Annotation from High-Resolution Data-Independent Acquisition Mass Spectrometry Analysis
by: Manuel D. Peris-Díaz, et al.
Published: (2019-09-01)

Brown Adipose Tissue Is Linked To A Distinct Thermoregulatory Response To Mild Cold In People
by: Maria eChondronikola, et al.
Published: (2016-04-01)

Dietary fatty acid metabolism of brown adipose tissue in cold-acclimated men
by: Denis P. Blondin, et al.
Published: (2017-01-01)

Cold and Exercise: Therapeutic Tools to Activate Brown Adipose Tissue and Combat Obesity
by: Carmem Peres Valgas da Silva, et al.
Published: (2019-02-01)

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation
by: Juliane Weiner, et al.
Published: (2017-06-01)

Thermogenesis and Fuel Selection During Cold Exposure: Tissue-Specific Metabolism and Cold-Acclimation.
by: Blondin, Denis
Published: (2014)

Thermogenesis and Fuel Selection During Cold Exposure: Tissue-Specific Metabolism and Cold-Acclimation.
by: Blondin, Denis
Published: (2014)

Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers
by: Gustavo Abreu-Vieira, et al.
Published: (2020-01-01)

The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice
by: Merel Defour, et al.
Published: (2018-04-01)

Metabolomics of the tumor microenvironment in pediatric acute lymphoblastic leukemia.
by: Stefano Tiziani, et al.
Published: (2013-01-01)

Integrated Proteomics and Metabolomics Analysis of Perirenal Adipose Tissue in Obese Rabbits Treated with a Restricted Diet
by: Jiahao Shao, et al.
Published: (2021-04-01)