Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit

Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit

The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise can attenuate the loss of muscle mass during severe energy deficit (5500 kcal/d...

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Bibliographic Details
Main Authors: Marcos Martin-Rincon, Alberto Pérez-López, David Morales-Alamo, Ismael Perez-Suarez, Pedro de Pablos-Velasco, Mario Perez-Valera, Sergio Perez-Regalado, Miriam Martinez-Canton, Miriam Gelabert-Rebato, Julian William Juan-Habib, Hans-Christer Holmberg, Jose A L Calbet
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Nutrients
Subjects:
autophagy-lysosome
caloric restriction
protein degradation
skeletal muscle
ubiquitin-proteasome
Online Access:https://www.mdpi.com/2072-6643/11/11/2824

Internet

https://www.mdpi.com/2072-6643/11/11/2824

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