Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

Lentiviruses have been extensively used as gene delivery vectors since the mid-1990’s. Usually derived from the human immunodeficiency virus (HIV) genome, they mediate efficient gene transfer to non-dividing cells, including neurons and glia in the adult mammalian brain. In addition, integration of...

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Bibliographic Details
Main Authors: Stephanie Margaret Hughes, Louise C. Parr-Brownlie, Clementine eBosch-Bouju, Lucia eSchoderboeck, Rachel eSizemore, Wickliffe eAbraham
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Lentivirus
optogenetics
confocal and electron microscopy)
temporal and spatial specificity
neuron phenotype
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00014/full

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