Reactive oxygen species-sensitive thioketal-linked mesoporous silica nanoparticles as drug carrier for effective antibacterial activity

Reactive oxygen species-sensitive thioketal-linked mesoporous silica nanoparticles as drug carrier for effective antibacterial activity

Mesoporous silica nanoparticles (MSNs) carrying gatekeepers that are stimuli-responsive are widely investigated for the controlled delivery of drug at target sites. In this study, thioketal (TK) functionalized methoxy poly(ethylene glycol) (mPEG-TK) as ROS-responsive gatekeeper is used to modify MSN...

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Bibliographic Details
Main Authors: Jinsong Li, Zhiyu Ding, Yuezhan Li, Jinglei Miao, Weiguo Wang, Keshav Nundlall, Shijie Chen
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Materials & Design
Subjects:
Mesoporous silica nanoparticles (MSNs)
ROS-sensitive
Controlled release
Antibacterial activity
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127520305566

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