Prognostic significance of MGMT promoter methylation in Egyptian GBM patients: A single-institution experience

Prognostic significance of MGMT promoter methylation in Egyptian GBM patients: A single-institution experience

Background: Glioblastoma Multiforme (GBM) is the highest-mortality tumor of the central nervous system. Epigenetic silencing of the MGMT gene by promoter methylation is associated with loss of MGMT expression and deficiency in MGMT mediated DNA repair, which is affiliated with improved survival in p...

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Bibliographic Details
Main Authors:	Rabab Abdel Moneim, Mohamed Abdel-Rafei, Hesham Hassan, Ibrahim El-Zawahry, Wedad Bassam Hashem
Format:	Article
Language:	English
Published:	West Asia Organization for Cancer Prevention 2018-02-01
Series:	Asian Pacific Journal of Cancer Biology
Online Access:	http://www.waocp.org/journal/index.php/apjcb/article/view/104

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