Prognostic significance of MGMT promoter methylation in Egyptian GBM patients: A single-institution experience
Background: Glioblastoma Multiforme (GBM) is the highest-mortality tumor of the central nervous system. Epigenetic silencing of the MGMT gene by promoter methylation is associated with loss of MGMT expression and deficiency in MGMT mediated DNA repair, which is affiliated with improved survival in p...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2018-02-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Online Access: | http://www.waocp.org/journal/index.php/apjcb/article/view/104 |