Pathways and Barriers for Ion Translocation through the 5-HT3A Receptor Channel.

Pentameric ligand gated ion channels (pLGICs) are ionotropic receptors that mediate fast intercellular communications at synaptic level and include either cation selective (e.g., nAChR and 5-HT3) or anion selective (e.g., GlyR, GABAA and GluCl) membrane channels. Among others, 5-HT3 is one of the mo...

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Bibliographic Details
Main Authors: Danilo Di Maio, Balasubramanian Chandramouli, Giuseppe Brancato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605793?pdf=render