Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance.

Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance.

Amyloid precursor protein (APP), a transmembrane glycoprotein, is well known for its involvement in the pathogenesis of Alzheimer disease of the aging brain, but its normal function is unclear. APP is a prominent component of the adult as well as the developing brain. It is enriched in axonal growth...

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Bibliographic Details
Main Authors: Lucas J Sosa, Jared Bergman, Adriana Estrada-Bernal, Thomas J Glorioso, John M Kittelson, Karl H Pfenninger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3653867?pdf=render

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