Hematopoietic Cell Transplantation for MHC Class II Deficiency
Major histocompatibility complex (MHC) class II deficiency is a rare and fatal primary combined immunodeficiency. It affects both marrow-derived cells and thymic epithelium, leading to impaired antigen presentation by antigen presenting cells and delayed and incomplete maturation of CD4+ lymphocyte...
Main Authors: | Su Han Lum, Benedicte Neven, Mary A. Slatter, Andrew R. Gennery |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-12-01
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Series: | Frontiers in Pediatrics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fped.2019.00516/full |
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