Non-linear parameter estimates from non-stationary MEG data

We demonstrate a method to estimate key electrophysiological parameters from resting state data. In this paper we focus on the estimation of head-position parameters. The recovery of these parameters is especially challenging as they are non-linearly related to the measured field. In order to do t...

Full description

Bibliographic Details
Main Authors: Juan David Martinez-Vargas, Jose David Lopez, Adam Baker, Mark William Woolrich, German Castellanos-Dominguez, Gareth Barnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00366/full
Description
Summary:We demonstrate a method to estimate key electrophysiological parameters from resting state data. In this paper we focus on the estimation of head-position parameters. The recovery of these parameters is especially challenging as they are non-linearly related to the measured field. In order to do this we use an empirical Bayesian scheme to estimate the cortical current distribution due to a range of laterally shifted head-models. We compare different methods of approaching this problem from the division of M/EEG data into stationary sections and performing separate source inversions, to explaining all of the M/EEG data with a single inversion. We demonstrate this through estimation of head position in both simulated and empirical resting state MEG data collected using a head-cast.
ISSN:1662-453X