Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold

Intracellular generation of gold nanoparticles has drawn attention but toxic effects have limited potential applications. Here, the authors report on the delivery of ionic gold with PEG resulting in faster synthesis and reduced toxicity due to lower concentrations of ionic gold required and explore...

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Main Authors:	Aaron S. Schwartz-Duval, Christian J. Konopka, Parikshit Moitra, Enrique A. Daza, Indrajit Srivastava, Elyse V. Johnson, Taylor L. Kampert, Stanley Fayn, Anand Haran, Lawrence W. Dobrucki, Dipanjan Pan
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-17595-6

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spelling	doaj-ed78eaa00a594fb28473531f16e63f692021-09-12T11:47:23ZengNature Publishing GroupNature Communications2041-17232020-09-0111111810.1038/s41467-020-17595-6Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic goldAaron S. Schwartz-Duval0Christian J. Konopka1Parikshit Moitra2Enrique A. Daza3Indrajit Srivastava4Elyse V. Johnson5Taylor L. Kampert6Stanley Fayn7Anand Haran8Lawrence W. Dobrucki9Dipanjan Pan10Department of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland Baltimore School of MedicineDepartment of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignCytoviva inc.Department of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignDepartment of Bioengineering, University of Illinois, Urbana-ChampaignIntracellular generation of gold nanoparticles has drawn attention but toxic effects have limited potential applications. Here, the authors report on the delivery of ionic gold with PEG resulting in faster synthesis and reduced toxicity due to lower concentrations of ionic gold required and explore potential applications.https://doi.org/10.1038/s41467-020-17595-6
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Aaron S. Schwartz-Duval Christian J. Konopka Parikshit Moitra Enrique A. Daza Indrajit Srivastava Elyse V. Johnson Taylor L. Kampert Stanley Fayn Anand Haran Lawrence W. Dobrucki Dipanjan Pan
spellingShingle	Aaron S. Schwartz-Duval Christian J. Konopka Parikshit Moitra Enrique A. Daza Indrajit Srivastava Elyse V. Johnson Taylor L. Kampert Stanley Fayn Anand Haran Lawrence W. Dobrucki Dipanjan Pan Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold Nature Communications
author_facet	Aaron S. Schwartz-Duval Christian J. Konopka Parikshit Moitra Enrique A. Daza Indrajit Srivastava Elyse V. Johnson Taylor L. Kampert Stanley Fayn Anand Haran Lawrence W. Dobrucki Dipanjan Pan
author_sort	Aaron S. Schwartz-Duval
title	Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
title_short	Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
title_full	Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
title_fullStr	Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
title_full_unstemmed	Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
title_sort	intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-09-01
description	Intracellular generation of gold nanoparticles has drawn attention but toxic effects have limited potential applications. Here, the authors report on the delivery of ionic gold with PEG resulting in faster synthesis and reduced toxicity due to lower concentrations of ionic gold required and explore potential applications.
url	https://doi.org/10.1038/s41467-020-17595-6
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Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold

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