Cost-utility analysis of genetic screening in families of patients with germline <it>MUTYH </it>mutations

<p>Abstract</p> <p>Background</p> <p>MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic <it>MUTYH </it>germline mutations have a risk of approximately 60% to develop colorectal carcinoma (CRC). In the genera...

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Bibliographic Details
Main Authors: Vasen Hans FA, Hes Frederik J, Nielsen Maartje, van den Hout Wilbert B
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/8/42