Interferon-independent STING signaling promotes resistance to HSV-1 in vivo
STING is considered central to antiviral immunity via induction of type 1 interferons, but can also activate autophagy. Here the authors made two mice with different STING mutations that differentially affect these antiviral responses, and surprisingly show that inhibiting STING-dependent type 1 int...
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Bibliographic Details
| Main Authors: |
Lívia H. Yamashiro,
Stephen C. Wilson,
Huntly M. Morrison,
Vasiliki Karalis,
Jing-Yi J. Chung,
Katherine J. Chen,
Helen S. Bateup,
Moriah L. Szpara,
Angus Y. Lee,
Jeffery S. Cox,
Russell E. Vance |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17156-x
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