Primary African American Endothelial Cells Exhibit Endothelial Dysfunction with an Exacerbated Inflammatory Profile and Blunted MMP-2 Activity

Primary African American Endothelial Cells Exhibit Endothelial Dysfunction with an Exacerbated Inflammatory Profile and Blunted MMP-2 Activity

Endothelial dysfunction is associated with the racial health disparity in vascular dysfunction in African Americans (AAs). Matrix Metalloproteinase (MMP)-2 is constitutively expressed in endothelial cells (EC) and is a biomarker that has been associated with hypertension, as its properties are invol...

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Bibliographic Details
Main Authors: Marc D. Cook, Chenyi Ling, Heather Grimm, Adelola Adeyemo, Maitha Aldokhayyil, Kevin Heffernan, Bo Fernhall, Michael Brown
Format: Article
Language:English
Published: Atlantis Press 2020-11-01
Series:Artery Research
Subjects:
Endothelial dysfunction
hypertension
inflammation
matrix metalloproteinase-2
racial difference
Online Access:https://www.atlantis-press.com/article/125946344/view

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