TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.

Hydrogen sulfide (H(2)S), which is produced endogenously from L-cysteine, is an irritant with pro-nociceptive actions. We have used measurements of intracellular calcium concentration, electrophysiology and behavioral measurements to show that the somatic pronociceptive actions of H(2)S require TRPA...

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Bibliographic Details
Main Authors: David A Andersson, Clive Gentry, Stuart Bevan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469557?pdf=render