The interrelationship between promoter strength, gene expression, and growth rate.

In exponentially growing bacteria, expression of heterologous protein impedes cellular growth rates. Quantitative understanding of the relationship between expression and growth rate will advance our ability to forward engineer bacteria, important for metabolic engineering and synthetic biology appl...

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Bibliographic Details
Main Authors: Matthew S Bienick, Katherine W Young, Justin R Klesmith, Emily E Detwiler, Kyle J Tomek, Timothy A Whitehead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4186888?pdf=render