Mutations in the Two-Component GluS-GluR Regulatory System Confer Resistance to β-Lactam Antibiotics in Burkholderia glumae

Mutations in the Two-Component GluS-GluR Regulatory System Confer Resistance to β-Lactam Antibiotics in Burkholderia glumae

Bacteria have specific signaling systems to overcome selective pressure, such as exposure to antibiotics. The two-component system (TCS) plays an important role in the development of antibiotic resistance. Using the rice pathogen Burkholderia glumae BGR1 as a model organism, we showed that the GluS...

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Bibliographic Details
Main Authors: Joan Marunga, Eunhye Goo, Yongsung Kang, Ingyu Hwang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
β-lactam resistance
β-lactamase
Burkholderia glumae
penicillin-binding protein
rice panicle blight
two-component systems
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.721444/full

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