DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW

The lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one...

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Main Author: Samer Mohammed
Format: Article
Language:English
Published: Education in Action Club 2021-03-01
Series:Global Journal of Public Health Medicine
Subjects:
Online Access:https://www.gjphm.org/index.php/gjphm/article/view/72
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spelling doaj-ed4f0b2feffb412b838d3c98e6d5c0262021-10-02T11:28:55ZengEducation in Action ClubGlobal Journal of Public Health Medicine2664-46572021-03-013127928810.37557/gjphm.v3i1.7262DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEWSamer Mohammed0College of Pharmacy , University of BaghdadThe lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one of those therapies. Although the results from retrospective studies are not strongly supportive of corticosteroid routine use in COVID-19 despite the signals for some benefits, the dedicated RECOVERY trial found a significant reduction in death with dexamethasone only in severe cases on a ventilator or moderate cases on supplemental oxygen therapy nevertheless, no benefit observed in mild to moderate cases requiring no oxygen. More studies are still necessary to substantiate conclusive use with dexamethasone in COVID-19. This narrative review attempts to summarize all available shreds of evidence from previously published research articles on the use of dexamethasone in COVID-19 pandemic treatment.https://www.gjphm.org/index.php/gjphm/article/view/72covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic.
collection DOAJ
language English
format Article
sources DOAJ
author Samer Mohammed
spellingShingle Samer Mohammed
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
Global Journal of Public Health Medicine
covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic.
author_facet Samer Mohammed
author_sort Samer Mohammed
title DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
title_short DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
title_full DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
title_fullStr DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
title_full_unstemmed DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
title_sort dexamethasone use in management of covid19: a review
publisher Education in Action Club
series Global Journal of Public Health Medicine
issn 2664-4657
publishDate 2021-03-01
description The lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one of those therapies. Although the results from retrospective studies are not strongly supportive of corticosteroid routine use in COVID-19 despite the signals for some benefits, the dedicated RECOVERY trial found a significant reduction in death with dexamethasone only in severe cases on a ventilator or moderate cases on supplemental oxygen therapy nevertheless, no benefit observed in mild to moderate cases requiring no oxygen. More studies are still necessary to substantiate conclusive use with dexamethasone in COVID-19. This narrative review attempts to summarize all available shreds of evidence from previously published research articles on the use of dexamethasone in COVID-19 pandemic treatment.
topic covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic.
url https://www.gjphm.org/index.php/gjphm/article/view/72
work_keys_str_mv AT samermohammed dexamethasoneuseinmanagementofcovid19areview
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