DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW
The lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one...
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doaj-ed4f0b2feffb412b838d3c98e6d5c0262021-10-02T11:28:55ZengEducation in Action ClubGlobal Journal of Public Health Medicine2664-46572021-03-013127928810.37557/gjphm.v3i1.7262DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEWSamer Mohammed0College of Pharmacy , University of BaghdadThe lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one of those therapies. Although the results from retrospective studies are not strongly supportive of corticosteroid routine use in COVID-19 despite the signals for some benefits, the dedicated RECOVERY trial found a significant reduction in death with dexamethasone only in severe cases on a ventilator or moderate cases on supplemental oxygen therapy nevertheless, no benefit observed in mild to moderate cases requiring no oxygen. More studies are still necessary to substantiate conclusive use with dexamethasone in COVID-19. This narrative review attempts to summarize all available shreds of evidence from previously published research articles on the use of dexamethasone in COVID-19 pandemic treatment.https://www.gjphm.org/index.php/gjphm/article/view/72covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Samer Mohammed |
spellingShingle |
Samer Mohammed DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW Global Journal of Public Health Medicine covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic. |
author_facet |
Samer Mohammed |
author_sort |
Samer Mohammed |
title |
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW |
title_short |
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW |
title_full |
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW |
title_fullStr |
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW |
title_full_unstemmed |
DEXAMETHASONE USE IN MANAGEMENT OF COVID19: A REVIEW |
title_sort |
dexamethasone use in management of covid19: a review |
publisher |
Education in Action Club |
series |
Global Journal of Public Health Medicine |
issn |
2664-4657 |
publishDate |
2021-03-01 |
description |
The lack of active 2019 coronavirus disease (COVID-19) pandemic treatment creates a challenge for researchers and scientists to find the most appropriate treatment for this disease. Dexamethasone, according to the findings of the RECOVERY clinical trial, declared mid-June 2020 in print media was one of those therapies. Although the results from retrospective studies are not strongly supportive of corticosteroid routine use in COVID-19 despite the signals for some benefits, the dedicated RECOVERY trial found a significant reduction in death with dexamethasone only in severe cases on a ventilator or moderate cases on supplemental oxygen therapy nevertheless, no benefit observed in mild to moderate cases requiring no oxygen. More studies are still necessary to substantiate conclusive use with dexamethasone in COVID-19. This narrative review attempts to summarize all available shreds of evidence from previously published research articles on the use of dexamethasone in COVID-19 pandemic treatment. |
topic |
covid-19, dexamethasone, acute respiratory distress syndrome, randomized controlled trial, steroids, pandemic. |
url |
https://www.gjphm.org/index.php/gjphm/article/view/72 |
work_keys_str_mv |
AT samermohammed dexamethasoneuseinmanagementofcovid19areview |
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