| Summary: | Jullia A Rosdahl, Divakar Gupta Department of Ophthalmology, Duke University, Durham, NC 27710, USACorrespondence: Jullia A RosdahlDepartment of Ophthalmology, Duke University, 2351 Erwin Road, DUMC 3802, Durham, NC 27710, USATel +1 919-684-8850Fax +1 919-681-8267Email Jullia.rosdahl@duke.eduAbstract: Glaucoma is a common blinding disease; while there is no cure, effective treatments include medications, laser, and incisional surgery. There is significant interest from patients and doctors to develop safer surgical options throughout the spectrum of disease, to minimize treatment burden in mild glaucoma patients and to minimize risk of complications in patients needing more aggressive treatment. Surgical procedures called Minimally or Micro-Invasive Glaucoma Surgery (MIGS) are growing in popularity. Eighty-seven prospective studies on MIGS were identified and assessed for quality. Most (74%) did not have a control group. Twelve of the highest quality were reviewed. MIGS procedures appeared to have fewer complications, and lowered intraocular pressure, and reduced medication use. Studies were limited by small sample size, narrow spectrum of glaucomatous disease, and/or conflicts of interest. There is a need for high quality, independently funded and performed, comparative studies on the MIGS to help make treatment decisions.Keywords: MIGS, angle surgery, ab interno, microinvasive, glaucoma treatment
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