Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

Lipid droplets (LDs) are cellular organelles dedicated to triacylglycerol storage that can undergo fusion and dissociation events. Here the authors show that formin-like 1-dependent acto-myosin assembly on LDs facilitates their dissociation and, as a consequence, affects hydrolysis and storage of tr...

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Bibliographic Details
Main Authors: Simon G. Pfisterer, Gergana Gateva, Peter Horvath, Juho Pirhonen, Veijo T. Salo, Leena Karhinen, Markku Varjosalo, Samppa J. Ryhänen, Pekka Lappalainen, Elina Ikonen
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14858