Duplex microRNAs assay based on target-triggered universal reporter hybridization

Duplex microRNAs assay based on target-triggered universal reporter hybridization

In this paper, we designed and evaluated a duplex detection strategy for microRNAs (miRNAs) using universal probe-based target-triggered double hybridization and fluorescent microsphere-based assay system (xMAP array). In the absence of target miRNA, reporter DNA cannot hybridize stably with the imm...

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Bibliographic Details
Main Authors: Yinan Wang, Yue Sun, Choiwan Lau, Jianzhong Lu
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177918301588

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