An Alternative to Dye-Based Approaches to Remove Background Autofluorescence From Primate Brain Tissue

Brain tissue contains autofluorescing elements that potentially impede accurate identification of neurons when visualized with fluorescent microscopy. Age-related accumulation of molecules with autofluorescent properties, such as lipofuscin, can possess spectral profiles that invade the typical emis...

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Bibliographic Details
Main Authors: Wonn S. Pyon, Daniel T. Gray, Carol A. Barnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnana.2019.00073/full