Prevalence of Anemia and Risk of Adverse Bleeding Effect of Drugs: Implication for Therapy

• Main Author: Ezekiel Uba Nwose
• Format: Article
• Language: English
• Published: Hindawi Limited 2012-01-01
• Series: Anemia
• Online Access: http://dx.doi.org/10.1155/2012/795439

This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data (𝑁=130,354) for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1% to 3.2% over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females (𝑃<0.0001), but protein level is lower in anemic females than in anemic males (𝑃<0.01). The results further show that up to 75% of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.