A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake1

A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake1

The class A macrophage scavenger receptors (SR-A) are macrophage-specific trimeric integral membrane glycoproteins that have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. There are two for...

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Bibliographic Details
Main Authors: Peter J. Gough, David R. Greaves, Siamon Gordon
Format: Article
Language:English
Published: Elsevier 1998-03-01
Series:Journal of Lipid Research
Subjects:
macrophage
scavenger receptor
alternative splicing
atherosclerosis
dominant negative mutant
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520332922

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http://www.sciencedirect.com/science/article/pii/S0022227520332922

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