Microgravity inhibits decidualization via decreasing Akt activity and FOXO3a expression in human endometrial stromal cells

Abstract Decidualization is characterized by the differentiation of endometrial stromal cells (eSCs), which is critical for embryo implantation and maintenance of pregnancy. In the present study, we investigated the possible effect of simulated microgravity (SM) on the process of proliferation and i...

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Bibliographic Details
Main Authors: Hye-Jeong Cho, Mi-Ock Baek, Sana Abdul Khaliq, Seung Joo Chon, Kuk Hui Son, Sung Ho Lee, Mee-Sup Yoon
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48580-9