Androgen Deficiency and Phosphodiesterase Type 5 Expression Changes in Aging Male: Therapeutic Implications

Androgen Deficiency and Phosphodiesterase Type 5 Expression Changes in Aging Male: Therapeutic Implications

The age-related decline of serum T occurs in ~20–30% of adult men and it is today defined as late-onset hypogonadism (LOH). In the elderly, such decline becomes more prevalent (up to 60%) and shows-up with erectile dysfunction (ED) and hypoactive sexual desire. A large body of experimental evidences...

Full description

Bibliographic Details
Main Authors: Antonio Aversa, Ylenia Duca, Rosita Angela Condorelli, Aldo Eugenio Calogero, Sandro La Vignera
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Endocrinology
Subjects:
aging
hypogonadism
erectile dysfunction
sexual desire
pde5 expression
pde5 inhibitors
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00225/full

Similar Items

Similar Items