Hypertensive emergency: A unique manifestation of a pituitary disorder

• Main Authors: Uday Yanamandra, Anantharam Jairam, Narendra Kotwal, Baliga Krishna Venkata, Velu Nair
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-01-01
• Series: Indian Journal of Endocrinology and Metabolism
• Subjects: Acromegaly; hypertensive emergency; hypertensive nephrosclerosis
• Online Access: http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=4;spage=747;epage=750;aulast=Yanamandra

Acromegaly a common pituitary disorder has significant adverse effects on well-being and survival. The slight increase in the prevalence of hypertension in acromegaly is well known and is proposed to be the direct effects of growth hormone. The hypertension for calculating the prevalence in most series was defined as diastolic more than 100 mmHg, but hypertensive emergency is rarely ever described in the literature. Growth hormone excess has been associated with renal manifestations such as hypercalciuria and nephrolithiasis, but never with renal failure. We present a case referred to a tertiary care nephrology center with malignant hypertension. This is the first case of a patient of acromegaly presenting with hypertensive emergency progressing to malignant nephrosclerosis and renal failure.