EIF4EBP1 overexpression is associated with poor survival and disease progression in patients with hepatocellular carcinoma.

EIF4EBP1 acts as a crucial effector in mTOR signaling pathway. Studies have suggested that EIF4EBP1 plays a critical role in carcinogenesis. However, the clinical significance and biological role of EIF4EBP1 in hepatocellular carcinoma (HCC) have not been elucidated. Therefore, we aimed to investiga...

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Bibliographic Details
Main Authors: Yin-Lian Cha, Pin-Dong Li, Lin-Jing Yuan, Mei-Yin Zhang, Yao-Jun Zhang, Hui-Lan Rao, Hui-Zhong Zhang, X F Steven Zheng, Hui-Yun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319970?pdf=render