A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus

A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus

Fungal infections caused by molds have the highest mortality rates of human fungal infections. These devastating infections are hard to treat and available antifungal drugs are often not effective.

Bibliographic Details
Main Authors: Sarah R. Beattie, Damian J. Krysan
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00539-21
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spelling doaj-ecfbbcd1876b44d8b4cad20ce187b2002021-09-21T19:41:35ZengAmerican Society for MicrobiologymSphere2379-50422021-08-016410.1128/mSphere.00539-21A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatusSarah R. Beattie0Damian J. Krysan1https://orcid.org/0000-0001-6330-3365Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USADepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA Fungal infections caused by molds have the highest mortality rates of human fungal infections. These devastating infections are hard to treat and available antifungal drugs are often not effective.https://journals.asm.org/doi/10.1128/mSphere.00539-21
collection DOAJ
language English
format Article
sources DOAJ
author Sarah R. Beattie
Damian J. Krysan
spellingShingle Sarah R. Beattie
Damian J. Krysan
A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
mSphere
author_facet Sarah R. Beattie
Damian J. Krysan
author_sort Sarah R. Beattie
title A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
title_short A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
title_full A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
title_fullStr A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
title_full_unstemmed A Unique Dual-Readout High-Throughput Screening Assay To Identify Antifungal Compounds with Aspergillus fumigatus
title_sort unique dual-readout high-throughput screening assay to identify antifungal compounds with aspergillus fumigatus
publisher American Society for Microbiology
series mSphere
issn 2379-5042
publishDate 2021-08-01
description Fungal infections caused by molds have the highest mortality rates of human fungal infections. These devastating infections are hard to treat and available antifungal drugs are often not effective.
url https://journals.asm.org/doi/10.1128/mSphere.00539-21
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