| Summary: | Background: The role of mineral components in the hemodynamic response to water drinking is still elusive. Methods: We conducted a randomized crossover study in 16 non-obese, healthy subjects (8 women) to investigate cardiovascular responses to water drinks differing in the mineral content. Continuous measurements included beat-to-beat blood pressure, electrocardiography derived RR-intervals, and impedance cardiography for a 30 min baseline period with a subsequent 60 min post-drink period. Results: In response to mineral water, but not distilled water, we observed significant time effects with decreases in heart rate and double product and increases in baroreflex sensitivity. Moreover, we observed a significant treatment difference in average heart rate responses starting 30 min after ingestion, where mineral water decreased heart rate to a greater extent than distilled water (p < 0.05). Conclusions: In young, healthy humans, drinking mineral water decreased heart rate in a time-dependent fashion, potentially due to its mineral properties.
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