Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation

Introduction: Calcium is vital for the functioning of the inner ear hair cells as well as for the neurotransmitter release that triggers the generation of a nerve impulse. A reduction in calcium level could therefore impair the peripheric vestibular functioning. However, the outcome of balance asses...

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Main Authors: Aditi Gargeshwari, Raghav Hira Jha, Niraj Kumar Singh, Prawin Kumar
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Brazilian Journal of Otorhinolaryngology
Online Access:http://www.sciencedirect.com/science/article/pii/S1808869417301568
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language English
format Article
sources DOAJ
author Aditi Gargeshwari
Raghav Hira Jha
Niraj Kumar Singh
Prawin Kumar
spellingShingle Aditi Gargeshwari
Raghav Hira Jha
Niraj Kumar Singh
Prawin Kumar
Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
Brazilian Journal of Otorhinolaryngology
author_facet Aditi Gargeshwari
Raghav Hira Jha
Niraj Kumar Singh
Prawin Kumar
author_sort Aditi Gargeshwari
title Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
title_short Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
title_full Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
title_fullStr Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
title_full_unstemmed Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
title_sort behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigation
publisher Elsevier
series Brazilian Journal of Otorhinolaryngology
issn 1808-8694
publishDate 2018-11-01
description Introduction: Calcium is vital for the functioning of the inner ear hair cells as well as for the neurotransmitter release that triggers the generation of a nerve impulse. A reduction in calcium level could therefore impair the peripheric vestibular functioning. However, the outcome of balance assessment has rarely been explored in cases with osteopenia and osteoporosis, the medical conditions associated with reduction in calcium levels. Objective: The present study aimed to investigate the impact of osteopenia and osteoporosis on the outcomes of behavioural and objective vestibular assessment tests. Methods: The study included 12 individuals each in the healthy control group and osteopenia group, and 11 individuals were included in the osteoporosis group. The groups were divided based on the findings of bone mineral density. All the participants underwent behavioural tests (Fukuda stepping, tandem gait and subjective visual vertical) and objective assessment using cervical and ocular vestibular evoked myogenic potentials. Results: A significantly higher proportion of the individuals in the two clinical groups’ demonstrated abnormal results on the behavioural balance assessment tests (p < 0.05) than the control group. However, there was no significant difference in latencies or amplitude of cervical vestibular evoked myogenic potential and oVEMP between the groups. The proportion of individuals with absence of ocular vestibular evoked myogenic potential was significantly higher in the osteoporosis group than the other two groups (p < 0.05). Conclusion: The findings of the present study confirm the presence of balance-related deficits in individuals with osteopenia and osteoporosis. Hence the clinical evaluations should include balance assessment as a mandatory aspect of the overall audiological assessment of individuals with osteopenia and osteoporosis. Resumo: Introdução: O cálcio é vital para o funcionamento das células ciliadas, assim como para a liberação dos neurotransmissores que desencadeiam um impulso nervoso. Uma redução nos níveis de cálcio poderia, portanto, prejudicar o funcionamento vestibular periférico. No entanto, a avaliação do equilíbrio tem sido raramente explorada em casos de osteopenia e osteoporose, condições médicas associadas à redução dos níveis de cálcio. Objetivo: O presente estudo teve como objetivo investigar o impacto da osteopenia e da osteoporose nos resultados dos testes de avaliação comportamental e vestibular objetiva. Método: O estudo incluiu 12 indivíduos nos grupos controle e grupo de osteopenia e 11 indivíduos no grupo da osteoporose. Os grupos foram divididos com base nos achados da densidade mineral óssea. Todos os participantes foram submetidos a testes comportamentais (Prova dos Passos de Fukuda, Marcha em tandem e Vertical Visual Subjetiva) e à avaliação objetiva com o uso de potenciais evocados miogênicos vestibulares cervical e ocular (cVEMP e oVEMP). Resultados: Uma proporção significativamente maior de indivíduos nos dois grupos com condições clínicas mostrou resultados anormais nos testes de avaliação comportamental e do equilíbrio (p < 0,05) do que o grupo controle. Embora não tenha havido diferença significativa nas latências ou na amplitude de cVEMP e oVEMP entre os grupos, a proporção de indivíduos com ausência de oVEMP foi significativamente maior no grupo da osteoporose do que nos outros dois grupos (p < 0,05). Conclusão: Os resultados do presente estudo demonstram a presença de déficits de equilíbrio em indivíduos com osteopenia e osteoporose. Assim, as avaliações clínicas gerais e audiológicas de indivíduos com osteopenia e osteoporose deveriam incluir a avaliação do equilíbrio como um aspecto obrigatório. Keywords: Osteoporosis, Osteopenia, Bone mineral density, cVEMP, oVEMP, Balance assessment, Palavras-chave: Osteoporose, Osteopenia, Densidade mineral óssea, cVEMP, oVEMP, Avaliação de equilíbrio
url http://www.sciencedirect.com/science/article/pii/S1808869417301568
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spelling doaj-ecd15801017a47358dcc3914f03120bc2021-02-02T08:54:18ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86942018-11-01846744753Behavioural and objective vestibular assessment in persons with osteoporosis and osteopenia: a preliminary investigationAditi Gargeshwari0Raghav Hira Jha1Niraj Kumar Singh2Prawin Kumar3All India Institute of Speech and Hearing, Department of Audiology, Manasagangothri, Karnataka, IndiaCorresponding author.; All India Institute of Speech and Hearing, Department of Audiology, Manasagangothri, Karnataka, IndiaAll India Institute of Speech and Hearing, Department of Audiology, Manasagangothri, Karnataka, IndiaAll India Institute of Speech and Hearing, Department of Audiology, Manasagangothri, Karnataka, IndiaIntroduction: Calcium is vital for the functioning of the inner ear hair cells as well as for the neurotransmitter release that triggers the generation of a nerve impulse. A reduction in calcium level could therefore impair the peripheric vestibular functioning. However, the outcome of balance assessment has rarely been explored in cases with osteopenia and osteoporosis, the medical conditions associated with reduction in calcium levels. Objective: The present study aimed to investigate the impact of osteopenia and osteoporosis on the outcomes of behavioural and objective vestibular assessment tests. Methods: The study included 12 individuals each in the healthy control group and osteopenia group, and 11 individuals were included in the osteoporosis group. The groups were divided based on the findings of bone mineral density. All the participants underwent behavioural tests (Fukuda stepping, tandem gait and subjective visual vertical) and objective assessment using cervical and ocular vestibular evoked myogenic potentials. Results: A significantly higher proportion of the individuals in the two clinical groups’ demonstrated abnormal results on the behavioural balance assessment tests (p < 0.05) than the control group. However, there was no significant difference in latencies or amplitude of cervical vestibular evoked myogenic potential and oVEMP between the groups. The proportion of individuals with absence of ocular vestibular evoked myogenic potential was significantly higher in the osteoporosis group than the other two groups (p < 0.05). Conclusion: The findings of the present study confirm the presence of balance-related deficits in individuals with osteopenia and osteoporosis. Hence the clinical evaluations should include balance assessment as a mandatory aspect of the overall audiological assessment of individuals with osteopenia and osteoporosis. Resumo: Introdução: O cálcio é vital para o funcionamento das células ciliadas, assim como para a liberação dos neurotransmissores que desencadeiam um impulso nervoso. Uma redução nos níveis de cálcio poderia, portanto, prejudicar o funcionamento vestibular periférico. No entanto, a avaliação do equilíbrio tem sido raramente explorada em casos de osteopenia e osteoporose, condições médicas associadas à redução dos níveis de cálcio. Objetivo: O presente estudo teve como objetivo investigar o impacto da osteopenia e da osteoporose nos resultados dos testes de avaliação comportamental e vestibular objetiva. Método: O estudo incluiu 12 indivíduos nos grupos controle e grupo de osteopenia e 11 indivíduos no grupo da osteoporose. Os grupos foram divididos com base nos achados da densidade mineral óssea. Todos os participantes foram submetidos a testes comportamentais (Prova dos Passos de Fukuda, Marcha em tandem e Vertical Visual Subjetiva) e à avaliação objetiva com o uso de potenciais evocados miogênicos vestibulares cervical e ocular (cVEMP e oVEMP). Resultados: Uma proporção significativamente maior de indivíduos nos dois grupos com condições clínicas mostrou resultados anormais nos testes de avaliação comportamental e do equilíbrio (p < 0,05) do que o grupo controle. Embora não tenha havido diferença significativa nas latências ou na amplitude de cVEMP e oVEMP entre os grupos, a proporção de indivíduos com ausência de oVEMP foi significativamente maior no grupo da osteoporose do que nos outros dois grupos (p < 0,05). Conclusão: Os resultados do presente estudo demonstram a presença de déficits de equilíbrio em indivíduos com osteopenia e osteoporose. Assim, as avaliações clínicas gerais e audiológicas de indivíduos com osteopenia e osteoporose deveriam incluir a avaliação do equilíbrio como um aspecto obrigatório. Keywords: Osteoporosis, Osteopenia, Bone mineral density, cVEMP, oVEMP, Balance assessment, Palavras-chave: Osteoporose, Osteopenia, Densidade mineral óssea, cVEMP, oVEMP, Avaliação de equilíbriohttp://www.sciencedirect.com/science/article/pii/S1808869417301568