N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity

N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity

The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray dif...

Full description

Bibliographic Details
Main Authors: Hui Zhao, Xiang-Peng Tan, Qi-An Peng, Cong-Zhong Shi, Yi-Fei Zhao, Yongming Cui
Format: Article
Language:English
Published: Slovenian Chemical Society 2020-06-01
Series:Acta Chimica Slovenica
Subjects:
hydrazone
copper complex
crystal structure
biological activity
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/5644
id doaj-eccbd9837e534d8da4f904c6b4f7de42
record_format Article
spelling doaj-eccbd9837e534d8da4f904c6b4f7de422020-11-25T02:58:36ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552020-06-0167263864310.17344/acsi.2019.5644827N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological ActivityHui Zhao0Xiang-Peng Tan1Qi-An Peng2Cong-Zhong Shi3Yi-Fei Zhao4Yongming Cui5Wuhan Textile UniversityWuhan Textile UniversityWuhan Textile UniversityWuhan Textile UniversityWuhan Textile UniversityWuhan Textile UniversityThe hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques. The complex is a thiocyanato-coordinated copper(II) species. The Cu atom in the complex is in square planar geometry. The complex is a promising urease inhibitor.https://journals.matheo.si/index.php/ACSi/article/view/5644hydrazonecopper complexcrystal structurebiological activity
collection DOAJ
language English
format Article
sources DOAJ
author Hui Zhao
Xiang-Peng Tan
Qi-An Peng
Cong-Zhong Shi
Yi-Fei Zhao
Yongming Cui
spellingShingle Hui Zhao
Xiang-Peng Tan
Qi-An Peng
Cong-Zhong Shi
Yi-Fei Zhao
Yongming Cui
N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
Acta Chimica Slovenica
hydrazone
copper complex
crystal structure
biological activity
author_facet Hui Zhao
Xiang-Peng Tan
Qi-An Peng
Cong-Zhong Shi
Yi-Fei Zhao
Yongming Cui
author_sort Hui Zhao
title N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
title_short N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
title_full N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
title_fullStr N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
title_full_unstemmed N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity
title_sort n'-(2-hydroxybenzylidene)-3-methylbenzohydrazide and its copper(ii) complex: syntheses, characterization, crystal structures and biological activity
publisher Slovenian Chemical Society
series Acta Chimica Slovenica
issn 1318-0207
1580-3155
publishDate 2020-06-01
description The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques. The complex is a thiocyanato-coordinated copper(II) species. The Cu atom in the complex is in square planar geometry. The complex is a promising urease inhibitor.
topic hydrazone
copper complex
crystal structure
biological activity
url https://journals.matheo.si/index.php/ACSi/article/view/5644
work_keys_str_mv AT huizhao n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
AT xiangpengtan n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
AT qianpeng n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
AT congzhongshi n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
AT yifeizhao n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
AT yongmingcui n2hydroxybenzylidene3methylbenzohydrazideanditscopperiicomplexsynthesescharacterizationcrystalstructuresandbiologicalactivity
_version_ 1724706171773779968

Similar Items