N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity

N'-(2-Hydroxybenzylidene)-3-methylbenzohydrazide and Its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity

The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray dif...

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Bibliographic Details
Main Authors: Hui Zhao, Xiang-Peng Tan, Qi-An Peng, Cong-Zhong Shi, Yi-Fei Zhao, Yongming Cui
Format: Article
Language:English
Published: Slovenian Chemical Society 2020-06-01
Series:Acta Chimica Slovenica
Subjects:
hydrazone
copper complex
crystal structure
biological activity
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/5644
Description
Summary:The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques. The complex is a thiocyanato-coordinated copper(II) species. The Cu atom in the complex is in square planar geometry. The complex is a promising urease inhibitor.
ISSN:1318-0207
1580-3155

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