Multiple effects of β-amyloid on single excitatory synaptic connections in the PFC

Multiple effects of β-amyloid on single excitatory synaptic connections in the PFC

Prefrontal cortex (PFC) is recognized as an AD-vulnerable region responsible for defects in cognitive functioning. Pyramidal cell (PC) connections are typically facilitating (F) or depressing (D) in PFC. Excitatory post-synaptic potentials (EPSPs) were recorded using patch-clamp from single connecti...

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Bibliographic Details
Main Authors: Yun eWang, Thomas Hongwei Zhou, Zhina eZhi, Amey eBarakat, Lynn eHlatky, Henry eQuerfurth
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
synaptic dynamics
β-amyloid (A)
Synaptic connection
excitatory post-synaptic potential (EPSP)
short term potentiation (STP)
synaptic augmentation (SA)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00129/full

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http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00129/full

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