RME-1 is required for lifespan extension and increased resistance to stresses associated with decreased insulin/IGF-1-like signaling in Caenorhabditis elegans

RME-1 is required for lifespan extension and increased resistance to stresses associated with decreased insulin/IGF-1-like signaling in Caenorhabditis elegans

The insulin/insulin-like growth factor (IGF)-1 signaling (IIS) pathway is a conserved life span-modulating genetic pathway. Many genes involved in lifespan extension associated with decreased signaling of the IIS pathway have been identified. In the present study, we found a novel gene requ...

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Bibliographic Details
Main Authors: Kim Chul-Kyu, Park Sang-Kyu
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2017-01-01
Series:Archives of Biological Sciences
Subjects:
C. elegans
insulin/IGF-1-like signaling pathway
lifespan
RME-1
stress response
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600115K.pdf

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