Downregulation of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia

Asthenozoospermia (AS), an important cause of male infertility, is characterized by reduced sperm motility. Among the aetiologies of AS, inflammation seems to be the main cause. DJ-1, a conserved protein product of the PARK7 gene, is associated with male infertility and plays a role in oxidative str...

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Bibliographic Details
Main Authors: Yupeng Wang, Yi Sun, Xin Zhao, Renpei Yuan, Hui Jiang, Xiaoping Pu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/6136075