Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase.

Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase.

Aberrant activation of PI3K/AKT signalling represents one of the most common molecular alterations in lung cancer, though the relative contribution of the single components of the cascade to the NSCLC development is still poorly defined. In this manuscript we have investigated the relationship betwe...

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Bibliographic Details
Main Authors: Marianna Scrima, Carmela De Marco, Fernanda Fabiani, Renato Franco, Giuseppe Pirozzi, Gaetano Rocco, Maria Ravo, Alessandro Weisz, Pietro Zoppoli, Michele Ceccarelli, Gerardo Botti, Donatella Malanga, Giuseppe Viglietto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281846?pdf=render

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http://europepmc.org/articles/PMC3281846?pdf=render

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