The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis

The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis

Abstract Emerging evidence suggested that epigenetic regulators can exhibit both activator and repressor activities in gene transcriptional regulation and disease development, such as cancer. However, how these dual activities are regulated and coordinated in specific cellular contexts remains elusi...

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Bibliographic Details
Main Authors: Hai‐feng Shen, Wen‐juan Zhang, Ying Huang, Yao‐hui He, Guo‐sheng Hu, Lei Wang, Bing‐ling Peng, Jia Yi, Ting‐ting Li, Rui Rong, Xiao‐yan Chen, Jun‐yi Liu, Wen‐juan Li, Kenny Ohgi, Shao‐Wei Li, Michael G. Rosenfeld, Wen Liu
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Advanced Science
Subjects:
breast cancer
estrogen and estrogen receptor
Jumonji C domain‐containing protein
type I interferon
Online Access:https://doi.org/10.1002/advs.202004635

Internet

https://doi.org/10.1002/advs.202004635

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