Decoding the Role of Sphingosine-1-Phosphate in Asthma and Other Respiratory System Diseases Using Next Generation Knowledge Discovery Platforms Coupled With Luminex Multiple Analyte Profiling Technology

Decoding the Role of Sphingosine-1-Phosphate in Asthma and Other Respiratory System Diseases Using Next Generation Knowledge Discovery Platforms Coupled With Luminex Multiple Analyte Profiling Technology

Sphingosine-1-phosphate (S1P) is a pleiotropic sphingolipid derived by the phosphorylation of sphingosine either by sphingosine kinase 1 (SPHK1) or SPHK2. Importantly, S1P acts through five different types of G-protein coupled S1P receptors (S1PRs) in immune cells to elicit inflammation and other im...

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Bibliographic Details
Main Authors: Sami Bahlas, Laila A. Damiati, Ayman S. Al-Hazmi, Peter Natesan Pushparaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
asthma
respiratory diseases
sphingosine-1-phosphate
SwissTargetPrediction
WebGestalt
open targets platform
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00444/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00444/full

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