The impact of chirality on the analysis of alkaloids in plant

Most of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention f...

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Main Authors: Ngoc-Van Thi Nguyen, Kim-Ngan Huynh Nguyen, Kien Trung Nguyen, Kyeong Ho Kim, Hassan Y. Aboul-Enein
Format: Article
Language:English
Published: Pensoft Publishers 2021-09-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/71101/download/pdf/
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spelling doaj-ec77524fd8b940cb84f94bcb843b2ccb2021-09-29T03:31:43ZengPensoft PublishersPharmacia2603-557X2021-09-0168364365610.3897/pharmacia.68.e7110171101The impact of chirality on the analysis of alkaloids in plantNgoc-Van Thi Nguyen0Kim-Ngan Huynh Nguyen1Kien Trung Nguyen2Kyeong Ho Kim3Hassan Y. Aboul-Enein4Can Tho University of Medicine and PharmacyCan Tho University of Medicine and PharmacyCan Tho University of Medicine and PharmacyKangwon National UniversityPharmaceutical and Drug Industries Research Division, National Research CenterMost of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention from pharmacological and toxicological points of view. This review gives an overview of the chiral analysis of alkaloids that were used in theoretical studies and applications for plants in recent years.https://pharmacia.pensoft.net/article/71101/download/pdf/
collection DOAJ
language English
format Article
sources DOAJ
author Ngoc-Van Thi Nguyen
Kim-Ngan Huynh Nguyen
Kien Trung Nguyen
Kyeong Ho Kim
Hassan Y. Aboul-Enein
spellingShingle Ngoc-Van Thi Nguyen
Kim-Ngan Huynh Nguyen
Kien Trung Nguyen
Kyeong Ho Kim
Hassan Y. Aboul-Enein
The impact of chirality on the analysis of alkaloids in plant
Pharmacia
author_facet Ngoc-Van Thi Nguyen
Kim-Ngan Huynh Nguyen
Kien Trung Nguyen
Kyeong Ho Kim
Hassan Y. Aboul-Enein
author_sort Ngoc-Van Thi Nguyen
title The impact of chirality on the analysis of alkaloids in plant
title_short The impact of chirality on the analysis of alkaloids in plant
title_full The impact of chirality on the analysis of alkaloids in plant
title_fullStr The impact of chirality on the analysis of alkaloids in plant
title_full_unstemmed The impact of chirality on the analysis of alkaloids in plant
title_sort impact of chirality on the analysis of alkaloids in plant
publisher Pensoft Publishers
series Pharmacia
issn 2603-557X
publishDate 2021-09-01
description Most of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention from pharmacological and toxicological points of view. This review gives an overview of the chiral analysis of alkaloids that were used in theoretical studies and applications for plants in recent years.
url https://pharmacia.pensoft.net/article/71101/download/pdf/
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