The impact of chirality on the analysis of alkaloids in plant
Most of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention f...
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2021-09-01
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doaj-ec77524fd8b940cb84f94bcb843b2ccb2021-09-29T03:31:43ZengPensoft PublishersPharmacia2603-557X2021-09-0168364365610.3897/pharmacia.68.e7110171101The impact of chirality on the analysis of alkaloids in plantNgoc-Van Thi Nguyen0Kim-Ngan Huynh Nguyen1Kien Trung Nguyen2Kyeong Ho Kim3Hassan Y. Aboul-Enein4Can Tho University of Medicine and PharmacyCan Tho University of Medicine and PharmacyCan Tho University of Medicine and PharmacyKangwon National UniversityPharmaceutical and Drug Industries Research Division, National Research CenterMost of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention from pharmacological and toxicological points of view. This review gives an overview of the chiral analysis of alkaloids that were used in theoretical studies and applications for plants in recent years.https://pharmacia.pensoft.net/article/71101/download/pdf/ |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ngoc-Van Thi Nguyen Kim-Ngan Huynh Nguyen Kien Trung Nguyen Kyeong Ho Kim Hassan Y. Aboul-Enein |
spellingShingle |
Ngoc-Van Thi Nguyen Kim-Ngan Huynh Nguyen Kien Trung Nguyen Kyeong Ho Kim Hassan Y. Aboul-Enein The impact of chirality on the analysis of alkaloids in plant Pharmacia |
author_facet |
Ngoc-Van Thi Nguyen Kim-Ngan Huynh Nguyen Kien Trung Nguyen Kyeong Ho Kim Hassan Y. Aboul-Enein |
author_sort |
Ngoc-Van Thi Nguyen |
title |
The impact of chirality on the analysis of alkaloids in plant |
title_short |
The impact of chirality on the analysis of alkaloids in plant |
title_full |
The impact of chirality on the analysis of alkaloids in plant |
title_fullStr |
The impact of chirality on the analysis of alkaloids in plant |
title_full_unstemmed |
The impact of chirality on the analysis of alkaloids in plant |
title_sort |
impact of chirality on the analysis of alkaloids in plant |
publisher |
Pensoft Publishers |
series |
Pharmacia |
issn |
2603-557X |
publishDate |
2021-09-01 |
description |
Most of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention from pharmacological and toxicological points of view. This review gives an overview of the chiral analysis of alkaloids that were used in theoretical studies and applications for plants in recent years. |
url |
https://pharmacia.pensoft.net/article/71101/download/pdf/ |
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