Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler

Background. Cellulitis is the inflammation of the skin and subcutaneous tissue. It is usually caused by Gram-positive organisms such as Staphylococcus and Streptococcus pyogenes infection. Nontypeable Haemophilus influenzae (NTHi) is an uncommon cause of cellulitis. Hence, we report on this case. Ca...

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Main Authors: Eiman Al Boloushi, Abdulla Al Amri, Ghassan Ghatasheh, Huda Al Dhanhani
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2019/8306491
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spelling doaj-ec7743ee361c404b8f7e5119ee6f9afd2020-11-25T01:08:44ZengHindawi LimitedCase Reports in Infectious Diseases2090-66252090-66332019-01-01201910.1155/2019/83064918306491Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy ToddlerEiman Al Boloushi0Abdulla Al Amri1Ghassan Ghatasheh2Huda Al Dhanhani3Academic Affair Department, Tawam Hospital, Al Ain, UAEGeneral Pediatrics Department, Tawam Hospital, Al Ain, UAEPediatrics Infectious Disease Department, Tawam Hospital, Al Ain, UAEPediatrics Infectious Disease Department, Tawam Hospital, Al Ain, UAEBackground. Cellulitis is the inflammation of the skin and subcutaneous tissue. It is usually caused by Gram-positive organisms such as Staphylococcus and Streptococcus pyogenes infection. Nontypeable Haemophilus influenzae (NTHi) is an uncommon cause of cellulitis. Hence, we report on this case. Case Presentation. A previously healthy 19-month-old girl presented with a fever and two-day history of progressive right leg swelling and redness. Her physical examination revealed significant induration and swelling of her right lower leg but no obvious signs of abscess formation. Given the clinical picture, she was admitted as a case of cellulitis. Parenteral clindamycin was started empirically, as the blood culture preliminary report showed Gram-negative rods. Ceftriaxone was added to broaden the coverage. Final blood culture grew NTHi. Despite the use of proper antibiotics (amoxicillin clavulanic acid), the clinical course was complicated with abscess formation that required surgical intervention. Conclusions. We are reporting a previously healthy child who developed NTHi cellulitis of the lower leg. To the best of our knowledge, there have been no formal reports pertaining to leg cellulitis following infection by NTHi, yet published in UAE, and reports of HIB cellulitis of the extremities still appear to be rare; hence, we report on this case.http://dx.doi.org/10.1155/2019/8306491
collection DOAJ
language English
format Article
sources DOAJ
author Eiman Al Boloushi
Abdulla Al Amri
Ghassan Ghatasheh
Huda Al Dhanhani
spellingShingle Eiman Al Boloushi
Abdulla Al Amri
Ghassan Ghatasheh
Huda Al Dhanhani
Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
Case Reports in Infectious Diseases
author_facet Eiman Al Boloushi
Abdulla Al Amri
Ghassan Ghatasheh
Huda Al Dhanhani
author_sort Eiman Al Boloushi
title Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
title_short Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
title_full Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
title_fullStr Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
title_full_unstemmed Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler
title_sort severe presentation of nontypeable haemophilus influenzae (nthi) infection in a previously healthy toddler
publisher Hindawi Limited
series Case Reports in Infectious Diseases
issn 2090-6625
2090-6633
publishDate 2019-01-01
description Background. Cellulitis is the inflammation of the skin and subcutaneous tissue. It is usually caused by Gram-positive organisms such as Staphylococcus and Streptococcus pyogenes infection. Nontypeable Haemophilus influenzae (NTHi) is an uncommon cause of cellulitis. Hence, we report on this case. Case Presentation. A previously healthy 19-month-old girl presented with a fever and two-day history of progressive right leg swelling and redness. Her physical examination revealed significant induration and swelling of her right lower leg but no obvious signs of abscess formation. Given the clinical picture, she was admitted as a case of cellulitis. Parenteral clindamycin was started empirically, as the blood culture preliminary report showed Gram-negative rods. Ceftriaxone was added to broaden the coverage. Final blood culture grew NTHi. Despite the use of proper antibiotics (amoxicillin clavulanic acid), the clinical course was complicated with abscess formation that required surgical intervention. Conclusions. We are reporting a previously healthy child who developed NTHi cellulitis of the lower leg. To the best of our knowledge, there have been no formal reports pertaining to leg cellulitis following infection by NTHi, yet published in UAE, and reports of HIB cellulitis of the extremities still appear to be rare; hence, we report on this case.
url http://dx.doi.org/10.1155/2019/8306491
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