SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER

Alkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of...

Full description

Bibliographic Details
Main Authors: T. I. Taradeyko, M. V. Sidorova, A. A. Iozep
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/628
id doaj-ec735be22baf4b9089bbfe6ad8dcdddc
record_format Article
spelling doaj-ec735be22baf4b9089bbfe6ad8dcdddc2021-07-28T13:06:56ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01041722628SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHERT. I. Taradeyko0M. V. Sidorova1A. A. Iozep2Saint-Petersburg State Chemical and Pharmaceutical UniversitySaint-Petersburg State Chemical and Pharmaceutical UniversitySaint-Petersburg State Chemical and Pharmaceutical UniversityAlkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of its esterification was investigated. The effect of acid concentration, reaction time and degree of carboxyethylation of the polysaccharide on the degree of esterification and the yield of the target product were shown.https://www.pharmjournal.ru/jour/article/view/628alginic acidcarboxyethyl alginic acidethyl ether of carboxyethyl alginic acid polymer analogous reaction
collection DOAJ
language Russian
format Article
sources DOAJ
author T. I. Taradeyko
M. V. Sidorova
A. A. Iozep
spellingShingle T. I. Taradeyko
M. V. Sidorova
A. A. Iozep
SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
Разработка и регистрация лекарственных средств
alginic acid
carboxyethyl alginic acid
ethyl ether of carboxyethyl alginic acid polymer analogous reaction
author_facet T. I. Taradeyko
M. V. Sidorova
A. A. Iozep
author_sort T. I. Taradeyko
title SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
title_short SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
title_full SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
title_fullStr SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
title_full_unstemmed SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
title_sort synthesis of carboxyethylalginic acid and its ethyl ether
publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
series Разработка и регистрация лекарственных средств
issn 2305-2066
2658-5049
publishDate 2019-01-01
description Alkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of its esterification was investigated. The effect of acid concentration, reaction time and degree of carboxyethylation of the polysaccharide on the degree of esterification and the yield of the target product were shown.
topic alginic acid
carboxyethyl alginic acid
ethyl ether of carboxyethyl alginic acid polymer analogous reaction
url https://www.pharmjournal.ru/jour/article/view/628
work_keys_str_mv AT titaradeyko synthesisofcarboxyethylalginicacidanditsethylether
AT mvsidorova synthesisofcarboxyethylalginicacidanditsethylether
AT aaiozep synthesisofcarboxyethylalginicacidanditsethylether
_version_ 1721276802684420096