The Effect of Endothelin-1 on Gene Expression of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase via Transforming Growth Factor Beta (TGF–β) Receptor in Human Aortic Smooth Muscle Cells

The Effect of Endothelin-1 on Gene Expression of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase via Transforming Growth Factor Beta (TGF–β) Receptor in Human Aortic Smooth Muscle Cells

Background: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) is one of the predominant sources of the production of free oxygen radicals in the vascular wall. Endothelin-1 is a potent vasoconstrictor factor that also has mitogenic activity in vascular smooth muscle cells. The activa...

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Bibliographic Details
Main Authors: Parisa Dayati, Reyhaneh Niayesh-Mehr, Alireza Jafari, Hossein Babaahmadi-Rezaei
Format: Article
Language:fas
Published: Vesnu Publications 2018-06-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
NADPH oxidase
Endothelin-1
Transforming growth factor beta
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/9631

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