Ultrasound-Triggered Effects of the Microbubbles Coupled to GDNF Plasmid-Loaded PEGylated Liposomes in a Rat Model of Parkinson's Disease

Ultrasound-Triggered Effects of the Microbubbles Coupled to GDNF Plasmid-Loaded PEGylated Liposomes in a Rat Model of Parkinson's Disease

Background: The purpose of this study was to investigate ultrasound-triggered effects of PEGylated liposomes-coupled microbubbles mediated gene transfer of glial cell line-derived neurotrophic factor (GDNF) plasmid (PLs-GDNF-MBs) on behavioral deficits and neuron loss in a rat model of Parkinson...

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Bibliographic Details
Main Authors:	Peijian Yue, Wang Miao, Lin Gao, Xinyu Zhao, Junfang Teng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-04-01
Series:	Frontiers in Neuroscience
Subjects:	GDNF microbubbles Parkinson's disease PEGylated liposomes ultrasound
Online Access:	http://journal.frontiersin.org/article/10.3389/fnins.2018.00222/full

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