Inhibition of Indoleamine 2,3 Dioxygenase Does Not Improve Cancer-Related Symptoms in a Murine Model of Human Papilloma Virus–Related Head and Neck Cancer

The expression of indoleamine 2,3 dioxygenase (IDO) by tumors can contribute to immunotolerance, and IDO induced by inflammation can also increase risk for the development of behavioral alterations. Thus, this study was initiated to determine whether IDO inhibition, intended to facilitate tumor clea...

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Bibliographic Details
Main Authors: Elisabeth G Vichaya, Daniel W Vermeer, David Budac, Anna Lee, Aaron Grossberg, Paola D Vermeer, John H Lee, Robert Dantzer
Format: Article
Language:English
Published: SAGE Publishing 2019-08-01
Series:International Journal of Tryptophan Research
Online Access:https://doi.org/10.1177/1178646919872508