Endocrinopathy Causing Skeletal Decalcification and Ectopic Calcification Highlighted by Imaging Tour
Primary Hyperparathyroidism (PHPT) is an endocrine disorder which is caused by increased production of Parathyroid Hormone (PTH). Hypercalcemia leads to a number of symptoms and may cause patient's morbidity and even mortality if left untreated. In the present case, a 21-year-old female prese...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2021-01-01
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Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://www.jcdr.net/articles/PDF/14417/46253_CE[Ra]_F(Sh)_PF1(AG_KM)_PFA(KM)_PN(KM).pdf |
Summary: | Primary Hyperparathyroidism (PHPT) is an endocrine disorder which is caused by increased production of Parathyroid Hormone
(PTH). Hypercalcemia leads to a number of symptoms and may cause patient's morbidity and even mortality if left untreated. In
the present case, a 21-year-old female presenting with frequent attacks of urinary tract infection, diffuse bone pain and episodic
pain abdomen since 15 months. On clinical, biochemical and radiological evaluation, the case was diagnosed as PHPT due to left
superior parathyroid adenoma. Patient underwent uneventful surgical parathyroidectomy following preoperative optimisation. She
achieved normocalcaemia without any surgical complications. This case is presented to highlight the impact of hyperparathyroidism
on calcium metabolism leading to extensive skeletal decalcification and ectopic deposition of calcium leading to end organ damage.
Various images are used to highlight this phenomenon of decalcification and calcification. |
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ISSN: | 2249-782X 0973-709X |