Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer

Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer

We present an integrative genome-wide analysis that can be used to predict the risk of progression from leukoplakia to oral squamous cell carcinoma (OSCC) arising in the gingivobuccal complex (GBC). We find that the genomic and transcriptomic profiles of leukoplakia resemble those observed in later...

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Bibliographic Details
Main Authors: Priyanka G. Bhosale, Simona Cristea, Srikant Ambatipudi, Rajiv S. Desai, Rajiv Kumar, Asawari Patil, Shubhada Kane, Anita M. Borges, Alejandro A. Schäffer, Niko Beerenwinkel, Manoj B. Mahimkar
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331730075X

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